NAD+ IV Therapy
NAD+ IV therapy is an intravenous infusion that supports the health and efficiency of your mitochondria, the structures inside every cell that produce its energy. NAD+ is a coenzyme those mitochondria depend on to do their work, and its availability declines with age. This infusion is directed at that decline.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.
What NAD+ actually does
NAD+ stands for nicotinamide adenine dinucleotide. It is not a vitamin or a hormone. It is a coenzyme present in every living cell, and it has two distinct roles that are worth separating.
The first is metabolic. NAD+ is a carrier in the reactions that convert nutrients into usable cellular energy. It shuttles electrons through glycolysis, the citric acid cycle, and oxidative phosphorylation in the mitochondria, cycling between its oxidized form, NAD+, and its reduced form, NADH. Without adequate NAD+, the machinery that produces ATP cannot run at capacity.
The second is regulatory. A family of enzymes called sirtuins, and another called PARPs, consume NAD+ as a substrate. Sirtuins are involved in mitochondrial quality control and metabolic regulation. PARPs are involved in DNA repair. Both draw down the same NAD+ pool, which means the pool is not only fuel for energy production but also the currency for cellular maintenance.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.
Why mitochondria are the focus
Mitochondrial efficiency sits at the center of current longevity science, and for a defensible reason.
Mitochondria produce the overwhelming majority of cellular ATP. They also accumulate damage over time. When damaged mitochondria build up faster than they are cleared, cells produce energy less cleanly, and the effect compounds across every tissue that depends on them, which is essentially all of them.
Cells have their own housekeeping system for this. Mitophagy is the process by which damaged mitochondria are identified and cleared. Mitochondrial biogenesis is the process by which new ones are built. Both are regulated by pathways that depend on NAD+ availability.
So the interest in NAD+ is not that it is an energy supplement in any casual sense. It is that it sits upstream of the machinery cells use to maintain their own mitochondria.
NAD+ sits upstream of the machinery cells use to maintain their own mitochondria.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.
The age-related decline
NAD+ availability is understood to decline with age. This has been observed across tissues and species, and it is one of the more consistently reported findings in the field.
Several mechanisms are proposed. Increased consumption by PARPs responding to accumulated DNA damage. Increased activity of enzymes such as CD38 that degrade NAD+. Reduced efficiency in the salvage pathways that recycle it.
What is well established is the observation of decline. What remains an active research question is how much restoring NAD+ availability changes downstream function in humans, and over what timeframe. The honest position is that this is a serious area of investigation rather than a settled one.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.
Why intravenous
Oral NAD+ precursors, including nicotinamide riboside and nicotinamide mononucleotide, are widely available and have been studied.
Intravenous delivery bypasses gastrointestinal absorption and first-pass hepatic metabolism, achieving different plasma concentrations than oral routes. That is a pharmacokinetic statement rather than a claim of superiority in outcome, and the comparative clinical question remains under study.
What IV administration does mean practically is that dosing is controlled, delivery is observed, and the infusion happens under clinical supervision as part of a coordinated program rather than as an unmonitored supplement regimen.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.
How it fits your program
Depending on your protocol, this infusion may be used during your preparation phase, around your clinical days, or as part of your longer term Healthspan Optimization.
Where it sits in your sequence is a physician driven decision informed by your baseline. Your Signature Lab Test includes mitochondrial markers among its panel, and those readings inform whether and when this is appropriate for you.
It is one component of a coordinated program, selected based on what your case calls for rather than applied by default to everyone.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.
What to expect
The infusion is delivered intravenously over a period determined by your protocol, and it is typically administered more slowly than many other IV therapies. Your care consultant will confirm the timing and what to expect on the day.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.
This infusion is directed at supporting normal cellular processes. It is not a cure for aging or for any condition.
It is described here in terms of the pathways it supports rather than results it delivers, because the human clinical evidence for downstream functional effects is still developing. Individual response cannot be predicted, and nothing here should be read as a claim that this treats, cures, or reverses anything.
Free consultation with a care consultant, many of our care consultants are registered nurses. No sales reps. No receptionist.